• any other medicines
• any other substances, such as foods, preservatives or dyes

Tell your doctor or pharmacist if you have pre-existing or a family history of hyperlipidemia (high cholesterol levels) or hypertriglyceridemia (high triglyceride levels in blood).

Tell your doctor or pharmacist if you are breast-feeding. Like most fertility medicines, It is not recommended while you are breast-feeding.

The chances of multiple pregnancies are higher when you use Clomid. You should be aware of the potential complications of multiple pregnancy before taking Clomid. Discuss this with your doctor.

How to take Clomid

How much to take

The recommended dose for the first course of It is one tablet per day for five days at the beginning of your cycle. If ovulation does not occur, your doctor may advise you to increase the dose of It in subsequent treatment cycles.

Do not take an increased dose unless instructed to do so by your doctor. Taking more than your doctor prescribes may overstimulate your ovaries, possibly damaging your ovaries and endangering your health.

Follow all directions given to you by your doctor and pharmacist carefully. These directions may differ from the information contained in this leaflet.

If you do not understand the instructions on the box, ask your doctor or pharmacist for help.

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When to take it

Your doctor will advise you on which day of your cycle to begin to take Clomid. If you do not have regular periods your doctor may prescribe other tablets e.g. norethisterone for a number of days, after which a period may start. Use this bleeding to time your Clomid course.

Take Clomid at about the same time each day. This will help you remember when to take the tablets.

How long to use it

It tablets are usually taken daily for five consecutive days at the beginning of your cycle.

Your doctor will advise you on how many courses of It, you should take.

Long term therapy with Clomid is not recommended. Your doctor will tell you for how long you should take Clomid.

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If you forget to take it

Do not take a double dose to make up for the dose that you missed. This may increase the chance of you getting an unwanted side effect.

If you take too much (overdose)

Immediately telephone your doctor or pharmacist or the Poisons Information Centre (telephone 13 11 26), or go to Accident and Emergency at your nearest hospital, if you think that you or anyone else may have taken too much Clomid. Do this even if there are no signs of discomfort or poisoning. You may need urgent medical attention.

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Clomid Progress Checks

It will be necessary to monitor your response to It. Methods used to do this include:

• basal body temperature chart
• urine testing
• blood tests
• mucus testing

The most appropriate method for you will be discussed by your doctor.

While you are using Clomid

Things you must not do

Do not give It to anyone else, even if they have the same condition as you.

Do not use It to treat any other complaints unless your doctor tells you to.

Things to be careful of

Be careful driving or operating machinery until you know how Clomid affects you. It may cause visual disturbances in some people. Make sure you know how you react to It before you drive a car, operate machinery, or do anything else that could be dangerous if you are dizzy or have blurred vision.

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Side effects

Tell your doctor or pharmacist as soon as possible if you do not feel well while you are taking It. It helps many people with infertility, but it may have unwanted side effects in a few people. All medicines can have side effects. Sometimes they are serious; most of the time they are not. You may need medical treatment if you get some of the side effects.

Tell your doctor or pharmacist if you notice any of the following:

• hot flushes
• intermenstrual (“between period”) spotting or heavy menstrual periods
• nausea or vomiting
• breast discomfort
• headache
• insomnia, nervousness, depression, fatigue, dizziness or light-headedness
• rash or skin irritations
• increased frequency of urination
• hair loss
• fever
• vaginal discharge
• seizures
• visual problems
• increased heart rate
• palpitations

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If any of the following happen, stop taking Clomid and tell your doctor or pharmacist immediately:

• blurred vision, spots or flashes
• abdominal discomfort or pelvic pain, soreness or a “bloated” feeling
• weight gain

The chances of ectopic pregnancies (foetus growing outside the womb) are higher if you conceive on It.

It may cause uterine fibroids to grow in size.

Prolonged It use may be associated with a small increase in the risk of ovarian cancer.

Hypertriglyceridemia (high triglyceride levels in blood) has been observed in patients who have pre-existing or a family history of hypertriglyceridaemia.

Other side effects not listed above may occur in some patients. Tell your doctor or pharmacist if you notice anything that is making you feel unwell.

Do not be alarmed by this list of possible side effects. You may not experience any of them.

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After using Clomid

Storage

Keep your tablets in the pack until it is time to take them. If you take the tablets out of the pack they will not keep well.

Keep your tablets in a cool dry place where the temperature stays below 25°C.

Do not store It or any other medicine in the bathroom or near a sink.

Do not leave it in the car on hot days or on window sills. Heat and dampness can destroy some medicines.

Keep it where children cannot reach it. A locked cupboard at least one-and-a-half metres above the ground is a good place to store medicines.

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Disposal

If your doctor or pharmacist tells you to stop taking Clomid or the tablets have passed their expiry date, ask your pharmacist what to do with any that are left over.